August 25, 2010
t: age of the allele (in generations), x(t): frequency of the allele in generation t, y: frequency of the allele in the ancestral chromosome, c: recombination rate between the two loci being used to define the allele. This equation can be used to estimate the age of alleles and is robust against past demographic history. Theory in population genetics and evolution provides some nice invariances that underly analysis. We usually are not so lucky to have such tools in personality psychology to guide our thinking. Montgomery Slatkin, Bruce Rannala. Estimating allele age. Annu Rev Genomics Hum Genet 2000 vol. 1 pp. 225-249

  • t: age of the allele (in generations),
  • x(t): frequency of the allele in generation t,
  • y: frequency of the allele in the ancestral chromosome,
  • c: recombination rate between the two loci being used to define the allele.

This equation can be used to estimate the age of alleles and is robust against past demographic history.

Theory in population genetics and evolution provides some nice invariances that underly analysis. We usually are not so lucky to have such tools in personality psychology to guide our thinking.

  • Montgomery Slatkin, Bruce Rannala. Estimating allele age. Annu Rev Genomics Hum Genet 2000 vol. 1 pp. 225-249

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Filed under: population genetics theory